Alzheimer’s Disease Detection Model Using Rotation Invariant DTCWT Features and Recurrent Neural Network With a Combination of LSTM and GRU

Authors

  • Preeti Topannavar Department of Electronics & Telecommunication Engineering, G. H. Raisoni College of Engineering and Management (Savitribai Phule University ), Pune 412207, Maharashtra, India
  • D. M. Yadav Department of Electronics & Telecommunication Engineering, G. H. Raisoni College of Engineering and Management (Savitribai Phule Pune University), Pune 412207, Maharashtra, India https://orcid.org/0000-0002-0376-9689
  • Varsha Bendre Department of Electronics & Telecommunication Engineering, Pimpri Chinchwad College of Engineering (Savitribai Phule Pune University), Pune 411044, Maharashtra, India https://orcid.org/0000-0003-0290-652X

DOI:

https://doi.org/10.26713/cma.v14i3.2457

Keywords:

Alzheimer’s disease, Dementia, RNN, LSTM, GRU, Performance parameters

Abstract

The characteristic features of brain magnetic resonance image (MRI) scans of Alzheimer’s disease (AD) patients and normal controls (NC) are difficult to differentiate because of very similar brain patterns and image intensities at the initial stages. Thus, it is difficult to detect AD at earlier stages. The earlier detection can lead to earlier medication for the patients to avoid further and permanent damage to their brains. Thus, computer-aided systems for early Alzheimer’s disease detection are needed. For this purpose, the lossless feature extraction method combined with feature reduction using a selection approach is one of the best possible solutions presented in this paper. The dataset used for experimentation for AD detection is a combination of MRI images with very mild and mild cognitive impairments. The 2D dual-tree complex wavelet transform (DTCWT) is used for feature extraction. A recurrent neural network (RNN) architecture is used for classification purposes. The long short-term memory (LSTM) and gated recurrent unit (GRU) are used in combination in the proposed architecture. The performance evaluation of combinations of LSTM and GRU and individual layers is performed, in which LSTM sandwiched between two GRU in the proposed model shows better performance.

Downloads

Download data is not yet available.

References

R. Alattas and B. D. Barkana, A comparative study of brain volume changes in Alzheimer’s disease using MRI scans, in: Proceedings of the 2015 Long Island Systems, Applications and Technology, Farmingdale, NY, USA, 2015, pp. 1 – 6, (2015), DOI: 10.1109/LISAT.2015.7160197.

Y. L. Chan, W. C. Ung, L. G. Lim, C.-K. Lu, M. Kiguchi and T. B. Tang, Automated thresholding method for fNIRS-based functional connectivity analysis: Validation with a case study on Alzheimer’s disease, IEEE Transactions on Neural Systems and Rehabilitation Engineering 28(8) (2020), 1691 – 1701, DOI: 10.1109/TNSRE.2020.3007589.

M. Dadar, T. A. Pascoal, S. Manitsirikul, K. Misquitta, V. S. Fonov, M. C. Tartaglia, J. Breitner, P. Rosa-Neto, O. T. Carmichael and C. Decarli, Validation of a regression technique for segmentation of white matter hyperintensities in Alzheimer’s disease, IEEE Transactions on Medical Imaging 36(8) (2017), 1758 – 1768, DOI: 10.1109/TMI.2017.2693978.

L. Du, F. Liu, K. Liu, X. Yao, S. L. Risacher, J. Han, A. J. Saykin and L. Shen, Associating multi-modal brain imaging phenotypes and genetic risk factors via a dirty multi-task learning method, IEEE Transactions on Medical Imaging 39(1) (2020), 3416 – 3428, DOI: 10.1109/TMI.2020.2995510.

F. Er and D. Goularas, Predicting the prognosis of MCI patients using longitudinal MRI data, IEEE/ACM Transactions on Computational Biology and Bioinformatics 18(3) (2021), 1164 – 1173, DOI: 10.1109/TCBB.2020.3017872.

L. J. Herrera, I. Rojas, H. Pomares, A. Guillén, O. Valenzuela and O. Baños, Classification of MRI images for Alzheimer’s disease detection, in: Proceedings of the 2013 International Conference on Social Computing, Alexandria, VA, USA, 2013, pp. 846 – 851, (2013), DOI: 10.1109/SocialCom.2013.127.

B. S. Khehra and A. P. S. Pharwaha, Comparison of genetic algorithm, particle swarm optimization and biogeography-based optimization for feature selection to classify clusters of microcalcifications, Journal of The Institution of Engineers (India): Series B 98(2) (2017), 189 – 202, DOI: 10.1007/s40031-016-0226-8.

A. Kulkarni and N. Kulkarni, Fuzzy neural network for pattern classification, Procedia Computer Science 167 (2020), 2606 – 2616, DOI: 10.1016/J.PROCS.2020.03.321.

C. Lian, M. Liu, Y. Pan and D. Shen, Attention-guided hybrid network for dementia diagnosis with structural MR images, IEEE Transactions on Cybernetics 52(4) (2022), 1992 – 2003, DOI: 10.1109/TCYB.2020.3005859.

B. S. Mahanand, S. Suresh, N. Sundararajan and M. A. Kumar, ICGA-ELM classifier for Alzheimer’s disease detection, in: Proceedings of 2013 Indian Conference on Medical Informatics and Telemedicine (ICMIT13), Kharagpur, India, pp. 48 – 52, (2013), DOI: 10.1109/IndianCMIT.2013.6529407.

A. V. Nandedkar and P. K. Biswas, A fuzzy min-max neural network classifier with compensatory neuron architecture, IEEE Transactions on Neural Networks 18(1) (2007), 42 – 54, DOI: 10.1109/TNN.2006.882811.

W. K. Oleiwi, Alzheimer disease diagnosis using the K-means, GLCM and K_NN, Journal of University of Babylon for Pure and Applied Sciences 26(2) (2017), 57 – 65, DOI: 10.29196/jub.v26i2.474.

P. K. Simpson, Fuzzy min-max neural networks. I. Classification, IEEE Transactions on Neural Networks 3(5) (1992), 776 – 786, DOI: 10.1109/72.159066.

M. E. Sweety and G. W. Jiji, Detection of Alzheimer disease in brain images using PSO and decision tree approach, in: 2014 IEEE International Conference on Advanced Communications, Control and Computing Technologies, Ramanathapuram, India, 2014, pp. 1305 – 1309, (2014), DOI: 10.1109/ICACCCT.2014.7019310.

S. Udomhunsakul and P. Wongsita, Feature extraction in medical ultrasonic image, in: Proceedings of the 3rd Kuala Lumpur International Conference on Biomedical Engineering 2006 (IFMBE’06), F. Ibrahim, N. A. A. Osman, J. Usman and N. A. Kadri (editors), Vol. 15, Springer, Berlin — Heidelberg (2007), DOI: 10.1007/978-3-540-68017-8_69.

S. Vetova and I. Ivanov, Image features extraction using the dual-tree complex wavelet transform, in: Advances in Applied and Pure Mathematics, J. Balicki (editor), pp. 277 – 282, WSEAS Press, (2014), URL: http://www.wseas.us/e-library/conferences/2014/Gdansk/MATH/MATH-37.pdf.

H. Zhang, J. Liu, D. Ma and Z. Wang, Data-core-based fuzzy min-max neural network for pattern classification, IEEE Transactions on Neural Networks 22(2) (2011), 2339 – 2352, DOI: 10.1109/TNN.2011.2175748.

Downloads

Published

18-10-2023
CITATION

How to Cite

Topannavar, P., Yadav, D. M., & Bendre, V. (2023). Alzheimer’s Disease Detection Model Using Rotation Invariant DTCWT Features and Recurrent Neural Network With a Combination of LSTM and GRU. Communications in Mathematics and Applications, 14(3), 1263–1273. https://doi.org/10.26713/cma.v14i3.2457

Issue

Section

Research Article