Assessing the Life Average Daily Dose (Ladd) due to Heavy Metal Contents in Water Samples from Covenant University, Canaanland, Ota, South West Nigeria

Omeje Maxwell, Olusegun O. Adewoyin, Emmanuel S. Joel, Andrew Uchegbu, Emenike Chidozie Praise God


The consumption of water with elevated concentration of lead (Pb) can prevent Hemoglobin Synthesis (Anemia) and results in Kidney diseases. A cross sectional study was conducted in to estimate the risk of exposure to lead via groundwater and bottled water ingestion pathway for the population of Covenant University, Canaanland, Ota, Ogun Sate using Perkin Elmer Optima 8000 ICP-OES. The concentration of Pb, Cr, Cd and As varies from water sample to another with the highest value of .7.07 $\mu$gL${}^{-1 }$ was noted in borehole water sample (BH1) behind John Hall. Comparing the value with the International recommended level by USEPA and WHO respectively, 7.07gL${}^{-1}$is less than 15$\mu$gL${}^{-1}$ and 10 $\mu$gL${}^{-1}$. The Life Average Daily Dose (LADD) estimated in this present study reported higher in BH1 for lead (Pb) and could pose health hazard if accumulated for a long time. This work suggest measures to employ quality water treatment plant to reduce the level of heavy metals in the selected water samples and also more research on radioisotopes in the same water samples.


Groundwater; Bottled water; Heavy metals ICP-OES; Chronic daily intake and hazard

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S.O. Adegoke, T.F.J. Dessauvagie and A.J. Whiteman, Macrofauna of Ewekoro Formation (Paleocene) of Southwest Nigeria, African Geology, University of Ibadan, 269 – 276 (1970).

American Academy of Pediatrics, Hospital discharge of the high-risk neonate, Pediatrics 102 (2) (1987), 411 – 417.

S. Arab and A. Alshikh, Estimating of some trace elements in mineral water in the Kingdom of Saudi Arabia, Life Science Journal 60 (7) (2010), 301 – 345.

ATSDR (2005), CDC Issues Recommendations for Lead Poisoning Prevention in Newly Arrived Refugee Children, Atlanta: Media Relations.

H.G. Billman, Offshore stratigraphy and paleontology of dahomey (Benin) embayment, NAPE Bulletin 70 (2) (1992), 121 – 130.

I. Borneff, Carcinogenic substances in water and soil, XXII, Mouse drinking study with 3,4- benzpyrene and potassium chromate, Archivfür Hygiene 152 (68) (1968), 45 – 53 (in German).

Canfield, Intellectual impairment in children with blood lead concentration below 10 microg per deciliter, National Instittue of Health 5 (2003).

N. Chiron, R. Guilet and E. Deydier, Adsorption of cu(II) and pb(II) onto a grafted silica: Isotherms and kinetic models, Water Research 37 (13) (2003), 3079 – 3086, S0043-1354(03)00156-8.

Colorado Department of Health (1990), Colorado case on jursdiction over hazardous waste cleanup, Radiation Control Divison, 283.

R. Dabeka, H. Conacher, J. Lawrence, W. Newsome, A. McKenzie, H. Wagner and K. Pepper, Survey of bottled drinking waters sold in Canada for chlorate, bromide, bromate, lead, cadmium and other trace elements, Food Additives & Contaminants 19 (2002), 721 – 732,

D. Caussy, Lessons from case studies of metals:investigating exposure bioavailability, and risk, Ecotoxicology and Enviromental Safety 47 (2) (2003), 45 – 51.

A. Demirak, F. Yilmaz, A. Levent Tuna and N. Ozdemir, Heavy metals in water, sediment and tissues of Leuciscuscephalus from a stream in south western Turkey, Chemosphere 63 (2006), 1451 – 1458,

D. Dogaru, J. Zobrist, D. Balteanu, C. Popescu, M. Sima, M. Amini and H. Yang, Community perception of water quality in a mining-affected area: A case study for the Certej catchment in the Apuseni Mountains in Romania, Environmental Management 43 (2009), 1131 – 1145,

J. Duruibe, M. Ogwuegbu and J. Egwurugwu, Heavy metal pollution and human biotoxic effects, International Journal of Physical Sciences 60 (2) (2007), 112 – 118.

A.D. Eaton, Standard Methods for the Examination of Water and Waste Water, 21st edn., American Public Health Association, Washington, ISBN 0875530478. pp. 343-453 (2005).

P.A. Feriance and T. Farewell Nystrom, The cadmium-stress stimulon of Escherichia coli K-12, Microbiol. 144 (1989), 1045–1050.

R. Fertmann, S. Hentschel, D. Dengler, U. Janßen and A. Lommel, Lead exposure by drinking water: An epidemiologial study in Hamburg, Germany, International Journal of Hygiene and Environmental Health 207 (3) (2004), 235 – 244,

M. Ghaderpoor, G. Jahed and S. Nazmara, Determination of toxic trace element in bottled waters consumption in the Tehran, Twelfth Environmental Health Engineering Congress (2009), Tehran, Iran.

EPA Guidelines for exposure assessment, Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC, EPA/600/Z-92/001, (1992).

B.B. Gump, P. Stewart, J. Reihman, E. Lonky, T. Darvill, P.J. Parsons et al., Low-level prenatal and postnatal blood lead exposure and adrenocortical responses to acute stress in children, Environmental Health Perspectives 116 (2) (2008), 249 – 255,

W.S. Hammond, Clinical data base management system, Springer 53 (7) (1882), 103.

M.Z. Hashmi, C. Yu, H. Shen, D. Duan, C. Shen, L. Lou and Y. Chen, Risk Assessment of Heavy Metals Pollution in Agricultural Soils of Siling Reservoir Watershed in Zhejiang Province, China, BioMed Research International (2013).

IARC, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 63, Dry Cleaning, Some Chlorinate Solvents and Other Industrial Chemicals, Lyon, p. 245.

A. Ikem, S. Odueyungbo, N.O. Egiebor and K. Nyavor, Chemical quality of bottled waters from three cities in eastern Alabama, Science of the Total Environment 285 (2002), 165 – 175,

P.M. Jakus, W.D. Shaw, T.N. Nguyen and M. Walker, Risk perceptions of arsenic in tap water and consumption of bottled water, Water Resources Research 45 (2) (2009), 121.

J.A. Janus and E.I. Krajnc, Integrated criteria document chromium: effects, Appendix, Bilthoven, Netherlands, National Institute of Public Health and Environmental Protection (1990).

H.A. Jones and R.D. Hockey, The geology of part of southwestern Nigerian, Bulletin of the Geological Survey of Nigeria 31 (4) (1964), 101 p.

T.A. Jusko, C.R. Henderson, B.P. Lanphear, D.A. Cory-Slechta, P.J. Parsons and R.L. Canfield, Blood lead concentrations Ç 10 microg/dL and child intelligence at 6 years of age, Environmental Health Perspectives 116 (2) (2008), 243 – 248,

P. Kavcar, A. Sofuoglu and S.C. Sofuoglu, A health risk assessment for exposure to trace metals via drinking water ingestion pathway, International Journal of Hygiene and Environmental Health 212 (2) (2009), 216 – 227,

B.P. Lanphear, K. Dietrich, P. Auinger and C. Cox, Cognitive deficits associated with blood lead concentrations Ç10 microg/dL in US children and adolescents, Public Health Reports (Washington, D.C.:1974) 115 (6) (2000), 521 – 529,

R.D. Mackenzie, Chronic toxicity studies - II, Hexavalent and trivalent Chromium administered in drinking water to rats, Archives of Industrial Health 18 (1958), 232 – 234.

B.A. Matte, Impact of lead contaminated Soil on Public Health, Springer (2) (1992), 147 – 151.

T. Matte and D. Jacobs, Housing and health — Current issues and implications for research and programs, Springer, New York (2000).

S. Muhammad, M.T. Shah and S. Khan, Arsenic health risk assessment in drinking water and source apportionment using multivariate statistical techniques in Kohistan region, northern Pakistan, Food Chem. Toxicol. 48 (3) (2010), 2855 – 2864.

S. Muhammad, M.T. Shah and S. Khan, Health risk assessment of heavy metals and their source apportionment in drinking water of Kohistan region, northern Pakistan, Microchemical Journal 98 (2011), 334 – 343,

NSDWQ, Nigerian Standard for Drinking Water Quality, Nigerian Industrial Standard 554 (2007), 13–14.

S.O. Olabode, Siliciclastic slope deposits from the Cretaceous Abeokuta Group, Dahomey (Benin) Basin, southwestern Nigeria, J. Afr. Earth Sci. 46 (2006), 187 – 200.

M.E. Omatsola and O.S. Adegoke, Tectonic evolution and Cretaceous stratigraphy of the Dahomey basin, Nigeria Geology 18 (51) (1981), 130 – 137.

P.C. Chrostowski, Exposure assessment principles, in Toxic Air Pollution Handbook, D.R. Patrick (ed.), Van Nostrand Reinhold, New York (1994), 133 – 163.

H. Pekey, D. Karaka¸s and M. Bakoglu, Source apportionment of trace metals in surface waters of a polluted stream using multivariate statistical analyses, Marine Pollution Bulletin 49 (2004), 809 – 818,

M.K. Raikwar, P. Kumar, M. Singh and A. Singh, Toxic effect of heavy metals in livestock health, Veterinary World 1 (2008), 28 – 30.

M. Robson, Methodologies for assessing exposures to metals: Human host factors, Ecotoxicology and Environmental Safety 56 (1) (2003), 104 – 109,

H.A. Schroeder and M. Mitchener, Scandium, chromium (VI), gallium, yttrium, rhodium, palladium, indium in mice: effects on growth and life span, Journal of Nutrition 101 (1971), 1431 – 1438.

W. Shotyk and M. Krachler, Lead in bottled waters: contamination from glass and comparison with pristine groundwater, Environmental Science & Technology 41 (2007), 3508 – 3513, United States.Environmental Protection Agency, Risk Assessment Forum (1999).

R.R. Engel and A.H. Smith, Arsenic in drinking water and mortality from vascular disease: an ecological analysis in 30 counties in the United States, Arch. Environ. Health 49 (1994), 418–427.

S. Szabó, G. Szabó, C. Fodor and L. Papp, Investigation of two sewage disposal sites from the aspect of environmental impacts on soil and groundwater in the County of Hajdú-Bihar (Hungary), Moravian Geographical Reports 16 (2008), 37–45.

B.J. Tola, Indicative of absorption and biological effect in new lead exposure, NCBI 2 (1973), 134 – 141.

USEPA, Integrated Exposure Uptake Bio-Kinetic model for Lead in Children (IEUBK), US Environmental Protection Agency (2012).

USEPA Environmental Protection Agency (EPA), Cancer risk coefficients for Environmental exposure to radionuclides, United State Environmental Protection Agency, Federal Guidance Report No. 13 (1999) (EPA. 402 R-99-001),

USEPA (United States Environmental Protection Agency), Risk assessment guidance for superfund: Human health evaluation manual (Part A), Washington, D.C.: United States Environmental Protection Agency 1 (1989), p. 248.

C.M. Villanueva, M. Kogevinas, S. Cordier, M.R. Templeton, R. Vermeulen, J.R. Nuckols, M.J. Nieuwenhuijsen and P. Levallois, Assessing exposure and health consequences of chemicals in drinking water: current state of knowledge and research needs, Environ. Health Perspect (2013)

Z. Wang, L. Chai, Y. Wang, Z. Yang, H. Wang and X. Wu, Potential health risk of arsenic and cadmium in groundwater near Xiangjiang River, China: a case study for risk assessment and management of toxic substances, Environmental Monitoring and Assessment 175 (2011), 167 – 173,

L.D. White, D.A. Cory-Slechta, M.E. Gilbert, E. Tiffany-Castiglioni, N.H. Zawia, M. Virgolini and R. Bashae, New and evolving concepts in the neurotoxicology of lead, Toxicology and Applied Pharmacology 225 (1) (2007), 1–27,

WHO, Guidelines for drinking-water quality: recommendations, World Health Organization (2004).

WHO, Guidelines for drinking-water quality: First addendum to volume 1, Recommendations, World Health Organization (2006).

World Health Organization, Guidelines for drinking-water quality, Vol. 2, health criteria and other supporting information, World Health Organization (1996).

K. Ye-Shin, P. Hoa-Sung, K. Jin-Yong, P. Sun-Ku, C. Byong-wook, S. Ig-hwan and S. Dong Chun, Health risk assessment for uranium in Korean groundwater, J. Environ. Radioct. 77 (1) (2004), 77–85.


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